|Report Code: PP10098||Report Type: Indication Pipeline Reports||Available format:|
Dravet syndrome is a form of severe myoclonic epilepsy that occurs in infants during their first year of age. If left untreated, it can be associated with other types of seizures, and status epilepticus. Children having Dravet syndrome are generally observed with poor cognitive skills and hyperactivity. It severely affects the person’s quality of life and around 10-20% of the patient are estimated to die due to the condition. Absence seizures, tonic-clonic seizures, atonic seizures, and myoclonic seizures are some other types of seizure associated with Dravet syndrome.
Zogenix Inc. is in the process of developing ZX008 as a serotonin receptor agonist for the treatment of Dravet syndrome. Ovid Therapeutics Inc. is also in the process of developing OV 935, a CH24H inhibitor, for the management of this medical condition. Insys Therapeutics Inc., and SAGE Therapeutics Inc. are some other major players having pipeline drugs for Dravet syndrome.