Pouchitis is an inflammatory disorder that develops when the ileal pouch becomes inflamed and irritated. Increased bowel frequency, bloody stool, incontinence, straining during defecation, tenesmus, lower abdominal pain and abdominal cramping or bloating are some of the problems observed in pouchitis. Colitis, familial adenomatous polyposis (FAP), ileal pouch-anal anastomosis (IPAA) surgery, inflamed and hardened bile ducts in the liver, use of nonsteroidal anti-inflammatory drugs (NSAIDs) and other conditions such as heart disease or diabetes are some of the major causes pouchitis. It is usually treated with antibiotics, probiotics, anti-diarrheal agents, low-carbohydrate and low-fiber diets. Atlantic Healthcare plc, and Avivia BV are two key companies involved in development of therapeutic agents for pouchitis.
The report provides a comprehensive understanding of the pipeline activities covering all drug candidates under various stages of development, with the detailed analysis of pipeline and clinical trials.
Pipeline analysis of drugs by phases includes product description and development activities including information about clinical results, designations, collaborations, licensing, grants, technology, and others.